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Mibefradil Oral
IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
MIBEFRADIL – ORAL
(my-BEFF-ruh-dill)
COMMON BRAND NAME: Posicor
USES: This drug is a calcium channel blocker. Calcium is involved in blood vessel contraction. By blocking calcium, mibefradil relaxes and widens the blood vessels. It is used to treat high blood pressure or chest pain (angina). This drug has been withdrawn from the U.S. market due to safety or effectiveness problems.
HOW TO USE: This drug is usually taken once daily by mouth. Follow directions exactly and do not stop taking this medication without first checking with your doctor or pharmacist. Tablets should be swallowed whole and not chewed or crushed. The full effect of the drug should occur after taking this for 1 to 2 weeks. When switching from mibefradil to certain other blood pressure medicines, it is advised to stop the mibefradil for a period of time before starting the new medicine. Consult your doctor.
SIDE EFFECTS: Generally this drug is well tolerated. Dizziness, headache, leg swelling, abdominal pain, nausea, unusual fatigue or nasal congestion might occur. If these persist or worsen, notify your doctor promptly. Very unlikely but report promptly: fainting spells, very slow heartbeat, breathing difficulties, skin rash. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), heart conditions, very low blood pressure, liver problems. To lessen the possible problem of feeling dizzy upon standing, stand up slowly from a lying or sitting position. This medication should be used only when clearly needed during pregnancy. Avoid use around the time of labor and birth. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medications you use, especially of: terfenadine, astemizole, cisapride, cyclosporine, tricyclic antidepressants (e.g., amitriptyline), tacrolimus, “statin” drugs (e.g., lovastatin), bepridil, cyclophosphamide, etoposide, erythromycin, flutamide, halofantrine, ifosfamide, pimozide, tamoxifen, thioridazine, vinblastine, vincristine. Also report the use of other heart drugs that affect the conduction system, such as: digoxin, beta-blockers (e.g., propranolol), other calcium blockers (e.g., verapamil), adenosine. If certain immunosuppressants (e.g., tacrolimus, cyclosporine) and any “statin” drugs for cholesterol are being used in combination, the manufacturer recommends avoiding mibefradil. The effects of mibefradil on other drugs can last for 14 days after stopping mibefradil. Consult your doctor or pharmacist. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, lightheadedness, and slow pulse.
NOTES: Do not share this medication with others.
MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not “double-up” the dose to catch up.
STORAGE: Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep container tightly closed.
Brand Name Mibefradil Oral drugs
Generic MIBEFRADIL - ORAL drugs
- Mibefradil Di H Cl Oral